Glypican 3 抗体
Quick Overview for Glypican 3 抗体 (ABIN1107403)
抗原
See all Glypican 3 (GPC3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Glypican-3 / GPC3.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Purified
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.05 % Sodium Azide, 0.5 % protein
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Glypican 3 (GPC3)
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别名
- Glypican-3 / GPC3
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背景
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5
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分子量
- 65.5 kDa
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基因ID
- 2719
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途径
- Glycosaminoglycan Metabolic Process
抗原
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