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Fibronectin 抗体

This anti-Fibronectin antibody is a 小鼠 单克隆 antibody detecting Fibronectin in WB, EIA 和 IHC (fro). Suitable for 人, 大鼠, 小鸡, 兔 和 豚鼠.
产品编号 ABIN1107236
发货至: 中国

Quick Overview for Fibronectin 抗体 (ABIN1107236)

抗原

See all Fibronectin 抗体
Fibronectin

适用

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人, 大鼠, 小鸡, 兔, 豚鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Fibronectin antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

DH1
  • 特异性

    The antibody is specific to extradomain A (EDA) sequence of a Cellular Fibronectin and recognizes thus only the Cellular Fibronectin (cFN). Clone DHI has been shown to specifically block Chondrocyte condensation in Chicken embryos (ref. 5).

    交叉反应 (详细)

    Species reactivity (tested):Human, Chicken, Rat, Rabbit and Guinea Pig.

    纯化方法

    Ig Fraction

    免疫原

    Purified Fibronectin from A8387 fibrosarcoma cells (ref. 21). Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.09 % (w/v) Sodium Azide, 1.0 % (w/v) BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    Fibronectin

    背景

    Fibronectins are diverse high molecular weight cell adhesion glycoproteins found in basement membranes, in the interstitial connective tissue matrix, and in soluble in plasma and other body fluids. In adult tissues most fibronectin is produced by hepatocytes (pFn) that differ from locally produced cellular fibronectins. A monoclonal antibody (AM32091PU-N Clone BF12) has been produced to fibronectin that reacts with both the cellular and plasma forms of the protein and recognizes the cell-binding region in fibronectin. The monoclonal antibody DH1 recognizes only cellular form of Fibronectin. DH1 is specific to the extra domain A (EDA) of the molecule. cFns are found in some basement membranes during development and only in distinct tissues in adult, for instance in smooth muscle and alveolar walls of airways. cFns are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas.Synonyms: CIG, Cold-insoluble globulin, FN1

    基因ID

    2335

    NCBI登录号

    NP_002017

    UniProt

    P02751
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