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Deoxyuridine Triphosphatase (DUT) (Middle Region) 抗体

DUT 适用: 人, 大鼠, 小鼠 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1107021
发货至: 中国
  • 抗原 See all Deoxyuridine Triphosphatase (DUT) 抗体
    Deoxyuridine Triphosphatase (DUT)
    抗原表位
    • 15
    • 15
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 75
    • 30
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 72
    • 2
    • 1
    克隆类型
    • 74
    • 1
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    非结合性
    应用范围
    • 64
    • 26
    • 26
    • 25
    • 22
    • 15
    • 7
    • 6
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    This antibody detects DUT in the middle. No cross reactivity with other roteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Immunogen affinity purified
    免疫原
    Synthetic peptide corresponding to a sequence mapping at the middle region of human dUTPase .Remarks: Sequence is identical to the related rat and ouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product DUT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg himerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Deoxyuridine Triphosphatase (DUT)
    别名
    DUT (DUT 产品)
    别名
    BcDNA:LD08534 antibody, CG4584 antibody, Dmel\\CG4584 antibody, LD08534 antibody, UTPase antibody, anon-SAGE:Wang-077 antibody, dUTPase antibody, Tb07.27E10.390 antibody, dutpase antibody, 5031412I06Rik antibody, 5133400F09Rik antibody, D2Bwg0749e antibody, Dutp antibody, PIP4 antibody, deoxyuridine triphosphatase antibody, Deoxyuridine triphosphatase antibody, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 antibody, involved in nucleotide metabolism antibody, tegument protein antibody, dUTPase antibody, deoxyuridine triphosphatase L homeolog antibody, DUT antibody, dUTPase antibody, P18 antibody, AlHV1gp51 antibody, UL50 antibody, HVT058 antibody, ORF9 antibody, ORF8 antibody, U45 antibody, GAMMAHV.ORF54 antibody, Tc00.1047053509151.130 antibody, Tc00.1047053508175.160 antibody, Tb927.7.5160 antibody, dut.L antibody, Dut antibody
    物质类
    Viral Protein
    背景
    Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low ntracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. DUTPase ctivity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and UTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the ytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35 % identity with the E. coli UTPase and 53 % identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial orms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the se of alternative 5-prime exons. Human dUTPase exhibits 92 % identity with rat. Moreover, this nzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis.Synonyms: Deoxyuridine 5'-triphosphate nucleotidohydrolase mitochondrial, dUTP pyrophosphatase, dUTPase
    基因ID
    1854
    NCBI登录号
    NP_001020419
    UniProt
    P33316
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