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Cytokeratin 13 抗体

This anti-Cytokeratin 13 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 13 in WB, IHC (p), IF, FACS 和 IHC (fro). Suitable for 人, 大鼠, 斑马鱼 和 Cat.
产品编号 ABIN1106904
发货至: 中国

Quick Overview for Cytokeratin 13 抗体 (ABIN1106904)

抗原

See all Cytokeratin 13 (KRT13) 抗体
Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

适用

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人, 大鼠, 斑马鱼, Cat

宿主

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 13 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

DE-K13
  • 特异性

    DE-K13 reacts with Cytokeratin 10 and 13 in fixed cells and on frozen tissues, but exclusively with cytokeratin 13 in Formalin-Fixed, Paraffin Embedded tissues. Cytokeratin 10 is present in keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas, while Cytokeratin 13 is present in noncornified squamous epithelia, except cornea, and transitional epithelial regions, with the exception of basal cell layers of some stratified epithelia, as well as carcinomas derived from these tissues.

    交叉反应 (详细)

    Species reactivity (tested):Human, Feline, Zebrafish.
    Also reacts to: KRT10

    纯化方法

    Purified

    免疫原

    Cytoskeletal preparation extracted from human ectocervical epithelium.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at -20 °C.
  • 抗原

    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

    别名

    Cytokeratin 13

    背景

    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK-13, CK13, K13, KRT-13, KRT13, Keratin type I cytoskeletal 13, Keratin-13

    基因ID

    3860

    NCBI登录号

    NP_002265

    UniProt

    P13646
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