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CXCR4 抗体 (C-Term)

This anti-CXCR4 antibody is a 兔 多克隆 antibody detecting CXCR4 in WB, IF, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1106858
发货至: 中国

Quick Overview for CXCR4 抗体 (C-Term) (ABIN1106858)

抗原

See all CXCR4 抗体
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CXCR4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    特异性

    This antibody detects endogenous levels of total CXCR4 protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide from Human CXCR4. Epitope: C-Terminus

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 50 % Glycerol, 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    别名

    CD184 / CXCR4

    背景

    CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor

    基因ID

    7852

    NCBI登录号

    NP_001008540

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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