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Corneodesmosin 抗体

This anti-Corneodesmosin antibody is a 兔 多克隆 antibody detecting Corneodesmosin in WB, EIA 和 IHC (fro). Suitable for 人.
产品编号 ABIN1106821
发货至: 中国

Quick Overview for Corneodesmosin 抗体 (ABIN1106821)

抗原

See all Corneodesmosin (CDSN) 抗体
Corneodesmosin (CDSN)

适用

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  • 3
  • 1

宿主

  • 14
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  • 3
  • 1

克隆类型

  • 19
  • 3
多克隆

标记

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  • 1
This Corneodesmosin antibody is un-conjugated

应用范围

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  • 13
  • 11
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Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    This antibody reacts with Human 51 kDa CDSN protein. May cross react with proteins from other species.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Synthetic peptide derived from N-termiknal domain of Human CDSN.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Corneodesmosin (CDSN)

    别名

    Corneodesmosin / CDSN

    背景

    Defects in CDSN are a cause of hypotrichosis simplex of the scalp (HTSS) [MIM:146520], also known as hypotrichosis Spanish type. HTSS is an autosomal dominant form of isolated alopecia. Affected individuals have normal hair in early childhood but experience progressive loss of scalp hair beginning in the middle of the first decade and almost complete baldness by the third decade. Defects in CDSN are the cause of peeling skin syndrome type B (BPSS) [MIM:270300], also known as peeling skin syndrome or deciduous skin or keratolysis exfoliativa congenita. BPSS is a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis, associated with pruritus and atopy. It is an ichthyosiform erythroderma characterized by lifelong patchy peeling of the entire skin with onset at birth or shortly thereafter. Several patients have been reported with high IgE levels.Synonyms: S protein

    基因ID

    1041

    NCBI登录号

    NP_001255
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