Corneodesmosin 抗体
Quick Overview for Corneodesmosin 抗体 (ABIN1106821)
抗原
See all Corneodesmosin (CDSN) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts with Human 51 kDa CDSN protein. May cross react with proteins from other species.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Synthetic peptide derived from N-termiknal domain of Human CDSN.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Corneodesmosin (CDSN)
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别名
- Corneodesmosin / CDSN
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背景
- Defects in CDSN are a cause of hypotrichosis simplex of the scalp (HTSS) [MIM:146520], also known as hypotrichosis Spanish type. HTSS is an autosomal dominant form of isolated alopecia. Affected individuals have normal hair in early childhood but experience progressive loss of scalp hair beginning in the middle of the first decade and almost complete baldness by the third decade. Defects in CDSN are the cause of peeling skin syndrome type B (BPSS) [MIM:270300], also known as peeling skin syndrome or deciduous skin or keratolysis exfoliativa congenita. BPSS is a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis, associated with pruritus and atopy. It is an ichthyosiform erythroderma characterized by lifelong patchy peeling of the entire skin with onset at birth or shortly thereafter. Several patients have been reported with high IgE levels.Synonyms: S protein
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基因ID
- 1041
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NCBI登录号
- NP_001255
抗原
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