Collagen Type V 抗体
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Quick Overview for Collagen Type V 抗体 (ABIN1106758)
抗原
See all Collagen Type V (COL5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody reacts with native Human as well as heat denatured Human Collagen type V in RIA, ELISA and immunoblot assays. The antibody does not react with Collagen types I, II, III and IV. Human plasma proteins do not interfere with binding to collagen.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- PEG6000 precipitation + Sepharose 6B gel filtration
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亚型
- IgM
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with 1 mL sterile water. Add preservative if preferred.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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: "Participation of collagen types I, III, IV, V, and fibronectin in the formation of villi fibrosis in human term placenta." in: Acta histochemica, Vol. 89, Issue 1, pp. 11-6, (1991) (PubMed).
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: "Participation of collagen types I, III, IV, V, and fibronectin in the formation of villi fibrosis in human term placenta." in: Acta histochemica, Vol. 89, Issue 1, pp. 11-6, (1991) (PubMed).
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- Collagen Type V (COL5) (Collagen, Type V (COL5))
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别名
- Collagen Type V
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背景
- Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1
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基因ID
- 1289
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NCBI登录号
- NP_000084
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UniProt
- P20908
抗原
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