Chips (C-Term) 抗体
适用: 哺乳动物
WB, IHC (p), IHC (fro), Func, EIA
宿主: 小鼠
Monoclonal
JCC1
unconjugated
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- 抗原
- Chips
- 抗原表位
- C-Term
-
适用
- 哺乳动物
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects with the C-terminus of CHIPS.
- 纯化方法
- Protein G purified
- 克隆位点
- JCC1
- 亚型
- IgG1
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.01 % sodium azide, 0.1 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 2-8 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
-
- 抗原
- Chips
- 别名
- NI36_09680 antibody, chemotaxis inhibitory protein antibody, NI36_RS09650 antibody
- 背景
- The bacterial pathogen Staphylococcus aureus is insensitive to antimicrobial host defense peptides such as defensins, protegrins, platelet microbicidal proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defense peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS (Chemotaxis Inhibiting Protein of Staphylococcus aureus). CHIPS is a protein produced by Staphylococcus aureus that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils. CHIPS and antibodies against CHIPS can be useful for various experimental infection models of Staphylococcus aureus. Furthermore these reagents can be of help in studies on the role of FPR and C5a in inflammatory processes.
- 基因ID
- 2861356
- NCBI登录号
- YP_041409
- UniProt
- Q6GFB3
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