CEP290 抗体 (C-Term)
Quick Overview for CEP290 抗体 (C-Term) (ABIN1106670)
抗原
See all CEP290 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with Mouse 290 kDa Cep290 protein.
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交叉反应 （详细）
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Species reactivity (expected):Rat, Human.
Species reactivity (tested):Mouse. -
纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Synthetic peptide derived from C-terminal domain of Mouse Cep290.
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anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibody
Verified CEP290 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyVerified CEP290 适用: 人 ELISA, IHC, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyCEP290 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyCEP290 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (AA 950-1050) antibodyCEP290 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore in distilled water.
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缓冲液
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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别名
- CEP290
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背景
- CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells, may play a role in ciliary transport processes. CEP290 is ubiquitously expressed, strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5) [MIM:610188], Senior-Loken syndrome type 6 (SLSN6) [MIM:610189], Leber congenital amaurosis type 10 (LCA10) [MIM:611755] and Meckel syndrome type 4 (MKS4) [MIM:611134]. Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.Synonyms: CT87, Cancer/testis antigen 87, Centrosomal protein of 290 kDa, KIAA0373, NPHP6, Nephrocystin-6, Tumor antigen se2-2, se2-2
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基因ID
- 216274
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NCBI登录号
- NP_666121
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途径
- cAMP Metabolic Process, M Phase
抗原
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