CEBPD 抗体 (N-Term)
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Quick Overview for CEBPD 抗体 (N-Term) (ABIN1106666)
抗原
See all CEBPD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody is specific for C/EBP delta protein. No cross-reactivity is observed with Mouse C/EBPalpha or C/EBPbeta.
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交叉反应 (详细)
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Species reactivity (expected):Human.
Species reactivity (tested):Mouse. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Recombinant protein corresponding to the amino terminus of Mouse C/EBP.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.83 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- CEBPD (CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD))
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别名
- CEBPD
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背景
- C/EBP proteins are DNA-binding proteins that are important transcriptional activators in the regulation of genes involved in immune and inflammatory responses and may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Members of the C/EBP transcription factor family are related by a high degree of amino acid sequence identity to the basic leucine zipper DNA-binding domain and show distinct but overlapping patterns of tissue- and stage-restricted expression. Osada et al. identified the consensus binding site for the family as RTTGCGYAAY (R = A or G, and Y = C or T). Phosphorylation of C/EBPdelta may increase binding activity, whereas phosphorylation of the alpha and beta family members may decrease binding affinity. C/EBPdelta is a nuclear protein that binds DNA as a dimer and can form stable heterodimers with all other C/EBP family members.Synonyms: C/EBP delta, CCAAT/enhancer-binding protein delta, NF-IL6-beta, Nuclear factor NF-IL6-beta
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基因ID
- 12609
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NCBI登录号
- NP_031705
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UniProt
- Q00322
抗原
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