CD96 抗体
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北京 101111
Quick Overview for CD96 抗体 (ABIN1106624)
抗原
See all CD96 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Monoclonal antibody NK92.39 reacts with CD96, also known as T cell-activated increased late expression (Tactile).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein G Chromatography
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8 °C.
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- CD96
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别名
- CD96
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背景
- CD96 promotes natural killer (NK) cell adhesion to target cells expressing the poliovirus receptor (PVR or CD155). Furthermore CD96 stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. This means NK cells have due to the receptor CD96 a dual receptor system that recognizes nectins and nectin-like molecules on target cells and mediates NK cells adhesion and triggering of effector functions. As PVR is highly expressed in certain tumors, this receptor system may be critical for NK cell recognition of tumors.Synonyms: Cell surface antigen CD96, T cell-activated increased late expression protein, T-cell surface protein tactile, TACTILE
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基因ID
- 10225
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NCBI登录号
- NP_005807
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UniProt
- P40200
抗原
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