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CD48 抗体

This 小鼠 单克隆 antibody specifically detects CD48 in FACS, WB, IP 和 IHC (p). It exhibits reactivity toward 人 和 灵长类.
产品编号 ABIN1106419
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CD48 抗体 (ABIN1106419)

抗原

See all CD48 抗体
CD48

适用

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人, 灵长类

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD48 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MEM-102
  • 特异性

    The antibody reacts with CD48 antigen (Blast-1), a 40-47 kDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells, it is negative on granulocytes, platelets and erythrocytes.

    纯化方法

    Protein-A affinity chromatography

    纯度

    > 95 % pure (by SDS-PAGE)

    免疫原

    Raji human Burkitt's lymphoma cell line

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. Dilute only prior to immediate use

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD48

    别名

    CD48

    背景

    CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases.Synonyms: B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, Leukocyte antigen MEM-102, MEM-102, TCT.1

    基因ID

    962

    NCBI登录号

    NP_001769

    UniProt

    P09326
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