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Integrin Alpha2b 抗体

The 小鼠 单克隆 anti-Integrin Alpha2b antibody (Clone CA3) (ABIN1106361) specifically detects Integrin Alpha2b in WB, IHC (fro) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN1106361
发货至: 中国
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Quick Overview for Integrin Alpha2b 抗体 (ABIN1106361)

抗原

See all Integrin Alpha2b (CD41) 抗体
Integrin Alpha2b (CD41)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin Alpha2b antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

CA3
  • 交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ig Fraction

    免疫原

    Partially purified platelet glycoprotein IIb/IIIa complex. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide, 1.0 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    Integrin Alpha2b (CD41)

    别名

    CD41 / ITGA2B

    背景

    Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation. The alpha IIb-Integrin subunit is a specific marker for platelets and megakaryocytes and can be utilized for this purpose in various immunological techniques.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

    基因ID

    9606

    UniProt

    P08514

    途径

    Integrin Complex
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