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CD38 抗体 (PerCP-Cy5.5)

适用: 人 FACS, IF 宿主: 小鼠 Monoclonal T16 PerCP-Cy5.5
产品编号 ABIN1106335
发货至: 中国
  • 抗原 See all CD38 抗体
    CD38
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD38 antibody is conjugated to PerCP-Cy5.5
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    Clone T16 produces mouse IgG1 immunoglobulins reactive with a 45 kDa antigen on lymphocytes [3]. CD38, clone T16, is widely used in flow cytometry to study T cell activation, B cell differentiation and in monitoring immunodeficiency diseases. CD38 is also reactive with multiple myelomas, most cases of ALL (both T and B lineage) and some cases of AML. In immunohistochemistry CD38, clone T16, reacts strongly with plasma cells and cortical thymocytes, less strongly with germinal center B cells. In clinical research CD38 is mainly used for leukemia and lymphoma typing and detection of plasma cells [4].
    纯化方法
    Affinity chromatography
    克隆位点
    T16
    亚型
    IgG1
    Top Product
    Discover our top product CD38 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
  • 抗原
    CD38
    Abstract
    CD38 产品
    背景
    CD38 is present in low density on human B cells and pre-B cells, subsets of CD4 and CD8 T cells, NK cells and monocytes. CD38 is also found in high density on Ig secreting plasma cells, germinal center B cells, mitogen-activated T cells, and several B and T cells. CD38 is a type II membrane glycoprotein, with the transmembrane sequence near the N-terminus. Antibodies to human CD38 have a wide range of biological effects, incuding the induction of B and T cell proliferation, protection of B cells from apoptosis, inhibition of B lymphopoiesis and enhancement of macrophage APC function [2].Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1
    基因ID
    952
    NCBI登录号
    NP_001766
    UniProt
    P28907
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