CD38 抗体 (APC)
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北京 101111
Quick Overview for CD38 抗体 (APC) (ABIN1106333)
抗原
See all CD38 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Clone T16 produces mouse IgG1 immunoglobulins reactive with a 45 kDa antigen on lymphocytes [3]. CD38, clone T16, is widely used in flow cytometry to study T cell activation, B cell differentiation and in monitoring immunodeficiency diseases. CD38 is also reactive with multiple myelomas, most cases of ALL (both T and B lineage) and some cases of AML. In immunohistochemistry CD38, clone T16, reacts strongly with plasma cells and cortical thymocytes, less strongly with germinal center B cells. In clinical research CD38 is mainly used for leukemia and lymphoma typing and detection of plasma cells [4].
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纯化方法
- Affinity chromatography
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亚型
- IgG1
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anti-CD38 (AA 1-300) antibody
适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 46-300) antibody适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 43-300) antibody适用: 人 IHC, WB, ELISA 宿主: 小鼠 Monoclonal 5C5C3 unconjugated
anti-CD38 (AA 241-270), (C-Term) antibody适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18001 unconjugated
anti-CD38 (AA 241-270) antibody适用: 人 FACS, IHC, WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 antibody适用: 人 FACS, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal HIT2 unconjugated
anti-CD38 antibody (APC)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 APC
anti-CD38 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 PE
anti-CD38 (AA 131-145), (Extracellular) antibody适用: 小鼠 FACS, IHC, WB, LCI 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 101-200) antibody适用: 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
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- CD38
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背景
- CD38 is present in low density on human B cells and pre-B cells, subsets of CD4 and CD8 T cells, NK cells and monocytes. CD38 is also found in high density on Ig secreting plasma cells, germinal center B cells, mitogen-activated T cells, and several B and T cells. CD38 is a type II membrane glycoprotein, with the transmembrane sequence near the N-terminus. Antibodies to human CD38 have a wide range of biological effects, incuding the induction of B and T cell proliferation, protection of B cells from apoptosis, inhibition of B lymphopoiesis and enhancement of macrophage APC function [2].Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1
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基因ID
- 952
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NCBI登录号
- NP_001766
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UniProt
- P28907
抗原
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