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F11R 抗体

This 大鼠 单克隆 antibody specifically detects F11R in IHC (fro). It exhibits reactivity toward 小鼠.
产品编号 ABIN1106263
发货至: 中国
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Quick Overview for F11R 抗体 (ABIN1106263)

抗原

See all F11R 抗体
F11R (F11 Receptor (F11R))

适用

  • 100
  • 55
  • 45
  • 9
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
小鼠

宿主

  • 91
  • 16
  • 14
  • 1
  • 1
大鼠

克隆类型

  • 61
  • 56
  • 3
单克隆

标记

  • 57
  • 10
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This F11R antibody is un-conjugated

应用范围

  • 86
  • 39
  • 31
  • 27
  • 25
  • 17
  • 15
  • 7
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

27-09-14
  • 纯化方法

    This antibody was purified from hybridoma (clone 27-9) supernatant using protein G agarose. This hybridoma was established by fusion of mouse myeloma cell P3X with Wister rat lymphocyte immunized with E14.5 mouse fetal liver cells.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2 containing no preservative

    储存液

    Without preservative
  • 抗原

    F11R (F11 Receptor (F11R))

    别名

    CD321 / JAM1

    背景

    Junctional adhesion molecules (JAMs) are member of the immunoglobulin superfamily. JAMs play an important role in many cellular processes such as tight junction assembly, leukocyte transmigration, platelet activation, angiogenesis and virus binding. JAM-A is a 37 kDa protein also called JAM-1 or F11R. JAM-A is expressed on endothelial cells, epithelial cells, and also hematopoietic cells such as neutrophils, platelets, monocytes, lymphocyte and erythrocyte. Extracellular domain of JAM-A participates in homophilic interaction stabilizing endothelial or epithelial cell-cell junctions particularly around tight junctions. In addition, JAM-A is important in leukocyte transmigration. Not only homophilic JAM-A interactions between leukocytes and the endothelium but also heterophilic interactions of JAM-A with the β2-integrin leukocyte function-associated antigen-1 (LFA-1) are considered to mediate leukocyte transmigration.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1

    途径

    Cell-Cell Junction Organization
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