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CD3 抗体

This anti-CD3 antibody is a 小鼠 单克隆 antibody detecting CD3 in IHC (fro). Suitable for 人 和 大鼠.
产品编号 ABIN1106240
发货至: 中国

Quick Overview for CD3 抗体 (ABIN1106240)

抗原

See all CD3 抗体
CD3

适用

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人, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD3 antibody is un-conjugated

应用范围

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Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

CA-3
  • 特异性

    This antibody reacts to CD3.

    纯化方法

    Affinity chromatography

    免疫原

    Human thymocytes followed by Sezary T cells.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.2 % sodium acetate or neutral PBS

    浓度

    0,1 mg/mL

    缓冲液

    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD3

    别名

    CD3

    背景

    The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3 (formerly T3).Human CD3 consists of at least 4 proteins: gamma, delta , epsilon, and zeta . The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

    基因ID

    916

    NCBI登录号

    NP_000724

    UniProt

    P07766

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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