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Leptin Receptor 抗体 (Soluble)

LEPR 适用: 人 WB, IHC (p), IHC (fro), EIA 宿主: 小鼠 Monoclonal 2F1 unconjugated
产品编号 ABIN1106239
发货至: 中国
  • 抗原 See all Leptin Receptor (LEPR) 抗体
    Leptin Receptor (LEPR)
    抗原表位
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    Soluble
    适用
    • 112
    • 70
    • 49
    • 20
    • 12
    • 5
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    宿主
    • 115
    • 14
    • 2
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    小鼠
    克隆类型
    • 112
    • 23
    单克隆
    标记
    • 48
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    This Leptin Receptor antibody is un-conjugated
    应用范围
    • 86
    • 46
    • 36
    • 36
    • 26
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    • 15
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    • 4
    • 4
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    克隆位点
    2F1
    亚型
    IgG1
    Top Product
    Discover our top product LEPR Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    Leptin Receptor (LEPR)
    别名
    CD295 / Leptin Receptor (LEPR 产品)
    别名
    CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody
    背景
    Leptin is a cytokine that is primarily expressed by adipose tissue. Leptin controls food intake by its interaction with the leptin receptor in the brain. Leptin action is mediated and controlled by the leptin receptor, a class I type cytokine receptor. sLR is generated by proteolytic cleavage of membrane-anchored receptors. This indicates that the leptin receptor might have other functions besides transduction. Binding of leptin with sLR increases the bioavailability of leptin in plasma, but also decreases the binding of leptin to membrane bound leptin receptors. For example, when comparing obese and lean individuals, plasma levels of sLR are significantly decreased whereas leptin levels are significantly increased.Synonyms: DB, HuB219, LEP-R, LEPR, OB receptor, OB-R, OBR
    基因ID
    9606
    UniProt
    P48357
    途径
    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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