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Leptin Receptor 抗体 (Soluble)

This anti-Leptin Receptor antibody is a 小鼠 单克隆 antibody detecting Leptin Receptor in WB, IHC (p), IHC (fro) 和 EIA. Suitable for 人.
产品编号 ABIN1106239
发货至: 中国

Quick Overview for Leptin Receptor 抗体 (Soluble) (ABIN1106239)

抗原

See all Leptin Receptor (LEPR) 抗体
Leptin Receptor (LEPR)

适用

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宿主

  • 119
  • 15
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  • 1
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小鼠

克隆类型

  • 113
  • 26
单克隆

标记

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This Leptin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

2F1
  • 抗原表位

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    Soluble

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein G

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2 - 8 °C.
  • 抗原

    Leptin Receptor (LEPR)

    别名

    CD295 / Leptin Receptor

    背景

    Leptin is a cytokine that is primarily expressed by adipose tissue. Leptin controls food intake by its interaction with the leptin receptor in the brain. Leptin action is mediated and controlled by the leptin receptor, a class I type cytokine receptor. sLR is generated by proteolytic cleavage of membrane-anchored receptors. This indicates that the leptin receptor might have other functions besides transduction. Binding of leptin with sLR increases the bioavailability of leptin in plasma, but also decreases the binding of leptin to membrane bound leptin receptors. For example, when comparing obese and lean individuals, plasma levels of sLR are significantly decreased whereas leptin levels are significantly increased.Synonyms: DB, HuB219, LEP-R, LEPR, OB receptor, OB-R, OBR

    基因ID

    9606

    UniProt

    P48357

    途径

    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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