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ITGB1 抗体

This anti-ITGB1 antibody is a 小鼠 单克隆 antibody detecting ITGB1 in WB, IHC (fro) 和 EIA. Suitable for 人.
产品编号 ABIN1106229
发货至: 中国

Quick Overview for ITGB1 抗体 (ABIN1106229)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

DF7
  • 交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ig Fraction

    免疫原

    Wheat germ agglutinin binding glycoproteins of Human fibroblasts. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide, 1.0 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    CD29 / Integrin beta-1

    背景

    CD29 or the integrin beta-1 belongs to the family of cell adhesion receptors. It was initially characterized independently as protein gpIIa appearing on platelets, as the common beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. The CD29 is expressed at the cell surface exclusively as part of a heterodimer, in association with one of at least nine different integrin alpha subunits (alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, alpha 6, alpha 7, alpha 8, and alpha v). With the exception of red blood cells and possible weak expression on granulocytes, CD29 is expressed nearly all cell and tissue types. Monoclonal antibodies against this β1-Integrin subunit are applicable in paraffin-embedded and frozen sections, immunoblotting and immunoprecipitation. Numerous studies have shown that β1 -Integrins have a distinct and wide cellular distribution and that there are alterations in malignant cells in their beta-1 integrin expression.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

    基因ID

    9606

    UniProt

    P05556

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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