电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PD-L1 抗体

PD-L1 适用: 人 FACS 宿主: 小鼠 Monoclonal MIH3 unconjugated
产品编号 ABIN1106177
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    适用
    • 167
    • 117
    • 62
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    宿主
    • 130
    • 55
    • 20
    • 4
    • 4
    • 2
    小鼠
    克隆类型
    • 111
    • 99
    • 5
    单克隆
    标记
    • 98
    • 15
    • 13
    • 10
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This PD-L1 antibody is un-conjugated
    应用范围
    • 129
    • 108
    • 59
    • 41
    • 40
    • 28
    • 18
    • 17
    • 15
    • 14
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody reacts with human CD274 antigen.
    纯化方法
    Protein A agarose
    免疫原
    Full-length human PD-L1 transfected L cells
    克隆位点
    MIH3
    亚型
    IgG1
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    CD274 / PDL1 (PD-L1 产品)
    背景
    Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunoglobulin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitro study indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-γ, GM-CSF and IL-10 from the T cells were enhanced.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
    基因ID
    29126
    NCBI登录号
    NP_054862
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
You are here:
客服