CD235a/GYPA 抗体
Quick Overview for CD235a/GYPA 抗体 (ABIN1106118)
抗原
See all CD235a/GYPA (GYPA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Clone NAM10-6G4 produces mouse IgG2a immunoglobulins directed against the human CD235a antigen (41 kDa) which is expressed as a cell surface sialoglycoprotein. This antibody may be effectively used for differentiation in acute leukemias, e.g. presence of the GpA antigen on leukemia cells indicates an early erythroid cell lineage of the tumor cells. Using the CD235a antibody, a distinction can be made between erythroleukemia and other (acute) leukemias like e.g. myeloid, lymphoid or undifferentiated leukemias [3,4]. CD235a is often used in combination with detection of H-antigen and/or anti-CD36 antibodies for additional characterization of early erythroid cells. Additional immunophenotyping of early erythroleukemias can be performed by detecting myeloid-associated antigens such as CD13, CD14, CD15, CD33 and CD34, to discriminate from lymphoid lineage-associated antigens like CD2, CD7, CD10 and CD19 [6].
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纯化方法
- Affinity chromatography
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亚型
- IgG2a
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anti-Glycophorin A (GYPA) (AA 20-91) antibody
GYPA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycophorin A (GYPA) (AA 1-108) antibodyGYPA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycophorin A (GYPA) antibodyGYPA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GYPA-280 unconjugated
anti-Glycophorin A (GYPA) (Internal Region) antibodyGYPA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycophorin A (GYPA) antibody (FITC)GYPA 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal JC159 FITC
anti-Glycophorin A (GYPA) antibody (PE)GYPA 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal JC159 PE
anti-Glycophorin A (GYPA) (C-Term) antibodyVerified GYPA 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glycophorin A (GYPA) antibodyGYPA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rGYPA-280 unconjugated Recombinant Antibody
anti-Glycophorin A (GYPA) antibodyGYPA 适用: 人, 大鼠 FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal JC159 unconjugated
anti-Glycophorin A (GYPA) (C-Term) antibodyGYPA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
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- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
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别名
- CD235a / GYPA
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背景
- Glycophorin A (GpA) antigen (CD235a) is exclusively expressed on human erythroid cells and their progenitors and not on lymphoid or granulocytic progenitor cells and therefore is a very useful marker for detection of the erythroid cell lineage [1,2]. CD235a seems to be absent from erythroid colony forming cells in bone marrow, but is present during maturation from (pro-)erythroid blast cells to mature erythrocytes. CD235a is clinically important in the classification of leukemias.Synonyms: GPA, Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha
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基因ID
- 2993
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NCBI登录号
- NP_002090
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UniProt
- P02724
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途径
- Maintenance of Protein Location
抗原
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