CXCR4 抗体
Quick Overview for CXCR4 抗体 (ABIN1105965)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes the soluble antigen. Recognizes the CXCR4 antigen, a 39.7 kDa protein.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ion Exchange Chromatography.
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过滤
- 0.22 μm filtered
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免疫原
- CXCR4 transfected CHO cell line. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
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亚型
- IgG1
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anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 201-294) antibody
CXCR4 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibodyCXCR4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 262-352) antibodyCXCR4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (N-Term) antibodyCXCR4 适用: 人, 小鼠, 兔, Pig, 马 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 14-40) antibodyCXCR4 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-356) antibodyCXCR4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (C-Term) antibodyCXCR4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibodyCXCR4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) antibody (PE)CXCR4 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 12G5 PE
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 2-15), (Extracellular) antibodyCXCR4 适用: 人 WB, IHC, FACS, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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别名
- CD184 / CXCR4
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背景
- CXCR4 (fusin, LESTR or HUMSTR) is a principal coreceptor for T cell tropic strains of HIV1 fusion and entry of human white blood cells. CXCR4 is also required for the infection by dual tropic strains of HIV1 and mediates CD4 independent infection by HIV2. The a chemokine SDF1 is the ligand for CXCR4 and prevents infection by T tropic HIV1. CXCR4 associates with the surface CD4-gp120 complex before HIV enters target cells. CXCR4 messenger RNA levels correlated with HIV1 permissiveness in diverse human cell types. Antibodies to CXCR4 block HIV1 and HIV2 fusion and infection of human target cells. The amino terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites. CXCR4 is highly expressed in brain and heart, and in white blood cells, vascular endothelial cells, and umbilical cord endothelial cells.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor
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基因ID
- 7852
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NCBI登录号
- NP_001008540
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UniProt
- P61073
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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