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CXCR4 抗体 (N-Term)

The 兔 多克隆 anti-CXCR4 antibody is suitable to detect CXCR4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN1105964
发货至: 中国
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Room 801-803
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Quick Overview for CXCR4 抗体 (N-Term) (ABIN1105964)

抗原

See all CXCR4 抗体
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CXCR4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    N-Term

    特异性

    This antibody detects CD184 / CXCR4 (N-term).

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat.

    纯化方法

    Immunogen affinity purified

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminal of human CXCR4 .Remarks: Sequence is different to the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    别名

    CD184 / CXCR4

    背景

    CXCR4 is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1, it functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. Tachibana et al. (1998) conclude that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor

    基因ID

    7852

    NCBI登录号

    NP_001008540

    UniProt

    P61073

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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