CD180 抗体 (Biotin)
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北京 101111
Quick Overview for CD180 抗体 (Biotin) (ABIN1105957)
抗原
See all CD180 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Mouse
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纯化方法
- Protein G
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亚型
- IgG2a
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anti-CD180 Molecule (CD180) (AA 24-220) antibody
CD180 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal G28-8 unconjugated
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal G28-8 unconjugated
anti-CD180 Molecule (CD180) (Internal Region) antibodyCD180 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) antibody (APC)CD180 适用: 人 FACS 宿主: 小鼠 Monoclonal G28-8 APC
anti-CD180 Molecule (CD180) antibody (PE)CD180 适用: 人 FACS 宿主: 小鼠 Monoclonal G28-8 PE
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) (C-Term) antibodyCD180 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) (N-Term) antibodyCD180 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
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有效期
- 6 months
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- CD180 (CD180 Molecule (CD180))
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别名
- CD180 / RP105
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背景
- Radioprotective 105 (RP105, CD180) is a type 1 transmembrane protein of 105 kDa with extracellular leucine-riche repeats (LLRs) and a short cytoplasmic tail. RP105, assigned as CD180, is similar to Drosophila Toll in the extracellular LLRs. Radioprotective 105 (RP105, CD180) expression is largely restricted to immune cells including CD19+ B cells and macrophages. Histological studies showed that RP105 is expressed mainly on mature B cells in mantle zones. Antibody-mediated (RP/14) cross-linking of RP105 induces resistance against irradiation-induced apoptosis, B-cell proliferation, and up-regulation of a costimulatory molecule B7.2, revealing RP105 as a potent regulator of B-cell activation. RP105 (CD180) has an important role in B-cell activation by LPS. It is important to note that RP105 associates with MD1, which is in this context important for RP105 with respect to B-cell surface expression and LPS recognition and signalling. MD-1 seems to be requisite for efficient expression of RP105.Synonyms: LY64, Lymphocyte antigen 64, Radioprotective 105 kDa protein
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基因ID
- 10090
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UniProt
- Q62192
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途径
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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