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- 抗原 See all CXCR4 抗体
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXCR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Neutralization (Neut)
- 特异性
- Cross-reactivity to CXCR4 of other species has not been determined.
- 免疫原
- This polyclonal antibody, which reacts with both rat and mouse CXCR4, was generated using E. coli-expressed rat CXCR4 as an immunogen.
- Top Product
- Discover our top product CXCR4 Primary Antibody
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- 应用备注
- The tested titer for Western blot is 1:2,000
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 储存条件
- 4 °C
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Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1705-15, (2010) (PubMed).
: "Human nephrosclerosis triggers a hypoxia-related glomerulopathy." in: The American journal of pathology, Vol. 176, Issue 2, pp. 594-607, (2010) (PubMed).
: "Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice." in: The Journal of clinical investigation, Vol. 120, Issue 3, pp. 694-705, (2010) (PubMed).
: "Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells." in: Circulation, Vol. 110, Issue 13, pp. 1847-54, (2004) (PubMed).
: "G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4." in: Nature immunology, Vol. 3, Issue 7, pp. 687-94, (2002) (PubMed).
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Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1705-15, (2010) (PubMed).
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- 抗原
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- 别名
- CXCR4 (CXCR4 产品)
- 背景
- CXCR4 (fusin) is one of the members in the seven-transmembrane G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library1. Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been proved to be the co-receptor for HIV?s binding to CD4 through envelope glycoprotein gp 1202. In other cases, CXCR4 can even function as the only receptor for HIV-2?s binding to the CD4 ? host cells3. Mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.
- 途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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