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CXCR4 抗体

CXCR4 适用: 小鼠, 大鼠 WB, FACS, Neut 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN110595
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    适用
    • 137
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    小鼠, 大鼠
    宿主
    • 117
    • 22
    • 10
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    • 1
    克隆类型
    • 126
    • 29
    多克隆
    标记
    • 94
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    This CXCR4 antibody is un-conjugated
    应用范围
    • 109
    • 50
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    Western Blotting (WB), Flow Cytometry (FACS), Neutralization (Neut)
    特异性
    Cross-reactivity to CXCR4 of other species has not been determined.
    免疫原
    This polyclonal antibody, which reacts with both rat and mouse CXCR4, was generated using E. coli-expressed rat CXCR4 as an immunogen.
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    The tested titer for Western blot is 1:2,000
    限制
    仅限研究用
  • 状态
    Lyophilized
    储存条件
    4 °C
  • Chen, Chemaly, Liang, Kho, Lee, Park, Altman, Schecter, Hajjar, Tarzami: "Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1705-15, (2010) (PubMed).

    Neusser, Lindenmeyer, Moll, Segerer, Edenhofer, Sen, Stiehl, Kretzler, Gröne, Schlöndorff, Cohen: "Human nephrosclerosis triggers a hypoxia-related glomerulopathy." in: The American journal of pathology, Vol. 176, Issue 2, pp. 594-607, (2010) (PubMed).

    Kioi, Vogel, Schultz, Hoffman, Harsh, Brown: "Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice." in: The Journal of clinical investigation, Vol. 120, Issue 3, pp. 694-705, (2010) (PubMed).

    Shyu, Lin, Yang, Tzeng, Pang, Yen, Li: "Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells." in: Circulation, Vol. 110, Issue 13, pp. 1847-54, (2004) (PubMed).

    Petit, Szyper-Kravitz, Nagler, Lahav, Peled, Habler, Ponomaryov, Taichman, Arenzana-Seisdedos, Fujii, Sandbank, Zipori, Lapidot: "G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4." in: Nature immunology, Vol. 3, Issue 7, pp. 687-94, (2002) (PubMed).

  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CXCR4 (CXCR4 产品)
    背景
    CXCR4 (fusin) is one of the members in the seven-transmembrane G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library1. Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been proved to be the co-receptor for HIV?s binding to CD4 through envelope glycoprotein gp 1202. In other cases, CXCR4 can even function as the only receptor for HIV-2?s binding to the CD4 ? host cells3. Mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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