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CXCR4 抗体

This anti-CXCR4 antibody is a 兔 多克隆 antibody detecting CXCR4 in WB, FACS 和 Neut. Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN110595
发货至: 中国

Quick Overview for CXCR4 抗体 (ABIN110595)

抗原

See all CXCR4 抗体
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CXCR4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Neutralization (Neut)
  • 特异性

    Cross-reactivity to CXCR4 of other species has not been determined.

    免疫原

    This polyclonal antibody, which reacts with both rat and mouse CXCR4, was generated using E. coli-expressed rat CXCR4 as an immunogen.
  • 应用备注

    The tested titer for Western blot is 1:2,000

    限制

    仅限研究用
  • 状态

    Lyophilized

    储存条件

    4 °C
  • Chen, Chemaly, Liang, Kho, Lee, Park, Altman, Schecter, Hajjar, Tarzami: "Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1705-15, (2010) (PubMed).

    Neusser, Lindenmeyer, Moll, Segerer, Edenhofer, Sen, Stiehl, Kretzler, Gröne, Schlöndorff, Cohen: "Human nephrosclerosis triggers a hypoxia-related glomerulopathy." in: The American journal of pathology, Vol. 176, Issue 2, pp. 594-607, (2010) (PubMed).

    Kioi, Vogel, Schultz, Hoffman, Harsh, Brown: "Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice." in: The Journal of clinical investigation, Vol. 120, Issue 3, pp. 694-705, (2010) (PubMed).

    Shyu, Lin, Yang, Tzeng, Pang, Yen, Li: "Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells." in: Circulation, Vol. 110, Issue 13, pp. 1847-54, (2004) (PubMed).

    Petit, Szyper-Kravitz, Nagler, Lahav, Peled, Habler, Ponomaryov, Taichman, Arenzana-Seisdedos, Fujii, Sandbank, Zipori, Lapidot: "G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4." in: Nature immunology, Vol. 3, Issue 7, pp. 687-94, (2002) (PubMed).

  • 抗原

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    别名

    CXCR4

    背景

    CXCR4 (fusin) is one of the members in the seven-transmembrane G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library1. Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been proved to be the co-receptor for HIV?s binding to CD4 through envelope glycoprotein gp 1202. In other cases, CXCR4 can even function as the only receptor for HIV-2?s binding to the CD4 ? host cells3. Mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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