CB43 recognizes the antigen CD147. This antigen is a single chain type I transmembrane with a MW of 50-60 kDa. It has been described as a tumor-cell-derived soluble factor that stimulates expression of collagenases by fibroblasts.
交叉反应 (详细)
Species reactivity (tested):Human.
纯化方法
Purified
免疫原
Native leucocytes. A BALB/c mouse was immunized. After three weeks the mouse was boosted and the splenocytes fused with myeloma cell line NSO. A positive hybridoma obtained after three limiting dilutions served as source for the hybridoma.