Thrombomodulin 抗体
Quick Overview for Thrombomodulin 抗体 (ABIN1105877)
抗原
See all Thrombomodulin (THBD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognises the soluble antigen. Recognises Thrombomodulin (TM), a 105 kDa protein.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Ion Exchange Chromatography
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过滤
- 0.22 μm filtered
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免疫原
- TF1 cell line.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, Sterile-filtered through 0.22 μm, Carrier and preservative free
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Thrombomodulin (THBD)
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别名
- CD141 / THBD
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背景
- CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII, thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.Synonyms: Fetomodulin, THRM, Thrombomodulin
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基因ID
- 7056
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NCBI登录号
- NP_000352
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UniProt
- P07204
抗原
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