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Syndecan 1 抗体

This anti-Syndecan 1 antibody is a 小鼠 单克隆 antibody detecting Syndecan 1 in FACS, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1105859
发货至: 中国

Quick Overview for Syndecan 1 抗体 (ABIN1105859)

抗原

See all Syndecan 1 (SDC1) 抗体
Syndecan 1 (SDC1)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Syndecan 1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

B-A38
  • 特异性

    The antibody B-A38 recognizes CD138 (Syndecan-1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Ion Exchange Chromatography

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Azide Free PBS, pH 7.4, 0.2 μm filter sterilized, None

    储存液

    Azide free
  • 抗原

    Syndecan 1 (SDC1)

    别名

    CD138 / Syndecan-1

    背景

    CD138 (syndecan-1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.Synonyms: SDC, SDC1, SYND1

    基因ID

    6382

    途径

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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