CD13 抗体
Quick Overview for CD13 抗体 (ABIN1105835)
抗原
See all CD13 (ANPEP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody ER-BMDM1 is directed against a 160- kDa cell membrane-associated antigen with aminopeptidase N activity. The antigen recognized by the mocnoclonal antibody ER-BMDM1 is present on various Mouse macrophage and dendritic cell subpopulations as well as on microvillous epithelia. The ER-BMDM1 antigen is expressed at increasing levels upon maturation of macrophages. Therefore the monoclonal antibody ER-BMDM1 is a useful marker for the identification of Aminopeptidase N positive macrophages and dendritic cells in Mouse, the expression of the ER-BMDM1 antigen arises after the monocytic stage of differentation: bone marrow cells and peripheral blood monocytes are ER-BMDM1 negative, whereas mature macrophages express the ER-BMDM1 antigen. A subpopulation of dendrocytes and their in vitro equivalents, the dendritic cells, are also ER-BMDM1 positive.
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交叉反应 （详细）
- Species reactivity (tested):Mouse.
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纯化方法
- Protein G Chromatography
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亚型
- IgG2a
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anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 668-967) antibody
ANPEP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 344-444) antibodyANPEP 适用: 人, 小鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 34-219) antibodyANPEP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibodyANPEP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibodyANPEP 适用: 人, Non-Human Primate FACS, IHC (fro), IP 宿主: 小鼠 Monoclonal WM15 unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibodyANPEP 适用: 人, Non-Human Primate FACS, IHC (fro), IP, Func 宿主: 小鼠 Monoclonal WM15 unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) (AA 781-967) antibodyANPEP 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1C7D7 unconjugated
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibody (Biotin)ANPEP 适用: 人, Non-Human Primate FACS, IHC (fro), IP 宿主: 小鼠 Monoclonal WM15 Biotin
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibody (FITC)ANPEP 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal WM15 FITC
anti-Alanyl (Membrane) Aminopeptidase (ANPEP) antibody (PE)ANPEP 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal WM15 PE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide, 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
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别名
- CD13
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背景
- Aminopeptidase N (APN) is also known as Alanyl Aminopeptidase (ANPEP), CD13 antigen or membrane protein p161. The protein consists of a short cyplasmic tail, a transmembrane region, a Ser/Thr region, and a zinc metalloproteinase domain. Widely expressed in many cells, tissues, and species, aminopeptidase N cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. It has putative involvement in several biological processes including antigen processing and presentation, cell adhesion, tumor invasion and metastasis and neurotransmitter degradation.Synonyms: ANPEP, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150
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基因ID
- 16790
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NCBI登录号
- NP_032512
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UniProt
- P97449
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途径
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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