ITGAL 抗体
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北京 101111
Quick Overview for ITGAL 抗体 (ABIN1105766)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody specifically detects CD11a positive leucocytes. CD11a antigens are expressed on lymphocytes, granulocytes, monocytes and macrophages with increased levels on memory T cells (1,2). Clone DF1524 was clustered at the Leucovyte Typing Workshop IV (5).
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纯化方法
- Affinity chromatography
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg / ml
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缓冲液
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a / ITGAL
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背景
- CD11a/CD18 was first described as an accessory molecule in cytotoxic lymphocyte killing. CD11a (Integrin alpha-L) combines with CD18 (Integrin beta-2) to form the integrin LFA-1. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligands. The avidity of CD11a to its ligands is transiently upregulated on T cells upon activation (3). CD11a has also been shown to bind bacterial lipopolysaccarides (4).Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
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基因ID
- 3683
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NCBI登录号
- NP_002200
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UniProt
- P20701
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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