Optimal working dilution should be determined by the investigator.
限制
仅限研究用
溶解方式
Restore with 1.2 % sodium acetate or neutral PBS.
浓度
0,1 mg/mL
缓冲液
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
Cathepsin L (CTSL1)
(Cathepsin L1 (CTSL1))
别名
Cathepsin L1
背景
Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins.Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein