BPDE-DNA 抗体
This anti-BPDE-DNA antibody is a 小鼠 单克隆 antibody detecting BPDE-DNA in EIA, IF, IHC (p) 和 IP. Suitable for 哺乳动物.
Quick Overview for BPDE-DNA 抗体 (ABIN1105553)
抗原
BPDE-DNA
(Benzo[a]pyrenediol Epoxide Modified DNA (BPDE-DNA))
适用
哺乳动物
宿主
小鼠
克隆类型
单克隆
应用范围
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
克隆位点
5D11
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纯化方法
- Protein G
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免疫原
- BPDE-I-DNA complexed with methylated BSA
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- BPDE-DNA (Benzo[a]pyrenediol Epoxide Modified DNA (BPDE-DNA))
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别名
- BPDE-DNA
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背景
- A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the malignant process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representative PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic.
抗原
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