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Hexosaminidase A 抗体

This anti-Hexosaminidase A antibody is a 小鼠 单克隆 antibody detecting Hexosaminidase A in WB, FACS 和 EIA. Suitable for 人.
产品编号 ABIN1105521
发货至: 中国

Quick Overview for Hexosaminidase A 抗体 (ABIN1105521)

抗原

See all Hexosaminidase A (HEXA) 抗体
Hexosaminidase A (HEXA)

适用

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宿主

  • 53
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小鼠

克隆类型

  • 55
  • 12
单克隆

标记

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This Hexosaminidase A antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

3F10
  • 特异性

    Recognizes Beta-hexosaminidase alpha / HEXA

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Purified

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    Hexosaminidase A (HEXA)

    别名

    beta-Hexosaminidase alpha / HEXA

    背景

    This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).Synonyms: Beta-N-acetylhexosaminidase subunit alpha, N-acetyl-beta-glucosaminidase subunit alpha

    分子量

    60.7 kDa

    基因ID

    3073

    途径

    Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
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