beta 2 Adrenergic Receptor 抗体
Quick Overview for beta 2 Adrenergic Receptor 抗体 (ABIN1105514)
抗原
See all beta 2 Adrenergic Receptor (ADRB2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody 6H8 recognizes Human beta-2-Adrenoceptor.
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交叉反应 （详细）
- Species reactivity (tested):Human, Rat, Guinea Pig.
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纯化方法
- Protein G
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免疫原
- Free peptide Beta2-H19C
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亚型
- IgG1
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anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 201-300) antibody
ADRB2 适用: 人, 大鼠, 小鼠 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (pSer346) antibodyADRB2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 302-413) antibodyADRB2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5G3B5 unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyADRB2 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 302-413) antibodyADRB2 适用: 人, 大鼠 宿主: 小鼠 Monoclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyVerified ADRB2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 1-413) antibodyADRB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (AA 1-413) antibodyADRB2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (C-Term) antibodyADRB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-2-, Receptor, Surface (ADRB2) (pSer346) antibodyADRB2 适用: 人, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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别名
- beta-2 Adrenergic Receptor
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背景
- The b -adrenoceptors can be divided into b1, b2, b3 and b4-adrenoceptors defined in terms of agonist potencies, b2-adrenoceptors displayed a higher selectivity for nor-adrenaline than for adrenaline. B2-receptors are mainly postsynaptic and are located on a number of tissues including blood vessels, bronchi, GIT, skeletal muscle, liver and mast cell. Activation results in vasodilatation, bronchodilation, relaxation of the GIT, glycogenolysis in the liver, tremor in skeletal muscle and inhibition of histamine release from mast cells. Transduction is via G-proteins coupled to the intracellular second messenger adenylate cyclase. B-receptors are positively coupled to adenylate cyclase via activation of Gs G-protein, however activation of the b2-adrenoceptors results in stimulation and inhibition of adenylate cyclase. The b2-receptor selective agonists are widely used in the treatment of asthma and other related bronchospastic conditions. They are commonly used in the treatment of angina pectoris, cardiac arrhythmia and for the long-term treatment of patients who survive myocardial infarction. B-receptor antagonists have also been used as anti-hypertensive for a number of years. Beta -blockers have also proven useful in the treatment of conditions such as migraine, anxiety disorders, hyperthyroidism, alcohol withdrawal and when applied topically are useful in the treatment of glaucoma and ocular hypertension.Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor
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基因ID
- 154
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NCBI登录号
- NP_000015
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UniProt
- P07550
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途径
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
抗原
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