Asialoglycoprotein Receptor 1 抗体
Quick Overview for Asialoglycoprotein Receptor 1 抗体 (ABIN1105447)
抗原
See all Asialoglycoprotein Receptor 1 (ASGR1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes a subunit-specific epitope on RHL-1 of rat ASGPR.
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交叉反应 （详细）
- Species reactivity (tested):Human, rat
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纯化方法
- Protein G
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亚型
- IgG1
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anti-Asialoglycoprotein Receptor 1 (ASGR1) (Middle Region) antibody
ASGR1 适用: 人, 小鼠, 大鼠, Cow, Pig, 豚鼠, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) (N-Term) antibodyASGR1 适用: 人, 小鼠, 大鼠, Cow, Pig, 豚鼠, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) (AA 77-289) antibodyASGR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) (AA 80-281) antibodyASGR1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) (AA 1-150) antibodyASGR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) (AA 201-291) antibodyASGR1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) (AA 68-291) antibodyASGR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) (AA 100-149) antibodyASGR1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Asialoglycoprotein Receptor 1 (ASGR1) antibody (FITC)ASGR1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Asialoglycoprotein Receptor 1 (ASGR1) antibody (Biotin)ASGR1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- Asialoglycoprotein Receptor 1 (ASGR1)
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别名
- ASGR1
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背景
- The asialoglycoprotein (ASGP) receptor is a transmembrane hepatocellular surface carbohydrate binding glycoproteins lacking terminal sialic acid residues (asialoglycoproteins). Characterization of the ASGP receptor revealed its functional role in the binding, internalization and transport of a wide range of glycoproteins, which have exposed galactose or N-acetylgalactosamine residues, via the process of receptor-mediated endocytosis (RME). The ASGP receptor can bind a variety of important plasma proteins including transport proteins (i.e. transferrin), enzymes such as alkaline phosphatase, immunoglobulins including IgA, apoptotic hepatocytes, fibronectin and platelets. Additionally, the expression of the ASGP receptor has been clinically correlated to the level of hepatic function that is lost during liver diseases related to cancer, viral hepatitis, and cirrhosis. The ASGP receptor consists of major and minor subunits, which in the rat were identified as rat hepatic lectin (RHL) 1 and RHL 2/3, with molecular weights of respectively 42, 49 and 54 kDa. The selective binding (calcium and pH depended) and uptake of terminal galactosyl bearing proteins requires the formation of hetero-oligomers between these major and minor forms The total ASGP receptor population consisted of two functionally distinct receptor populations, designated State 1 and State 2, which were involved in the endocytosis and intracellular processing of ligands by different pathways.Synonyms: ASGP-R 1, ASGPR 1, Asialoglycoprotein receptor 1, Hepatic lectin H1
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基因ID
- 24210
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NCBI登录号
- NP_036635
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UniProt
- P02706
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途径
- Thyroid Hormone Synthesis
抗原
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