SDF1 beta 抗体
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北京 101111
Quick Overview for SDF1 beta 抗体 (ABIN110541)
抗原
See all SDF1 beta (SDF1b) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Cross-reactivity to SDF-1b of other species has not been determined
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免疫原
- This polyclonal antibody, which reacts with both mouse and rat SDF-1b, was generated using E. coli-expressed mouse SDF-1b as an immunogen.
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亚型
- IgG
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应用备注
- The tested titer for Western blot is 1:1,000, immunoprecipitation, 1:300-500; and immunohistochemistry, 1:100-500.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- 1mg/ml
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储存条件
- 4 °C
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- SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))
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别名
- SDF-1 beta (Stromal Cell-Derived Factor, PBSF)
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背景
- SDF-1ß (stromal cell-derived factor-ß )1, also known as pre-B-cell growth-stimulating factor (PBSF)2, is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line1. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice3. SDF-1 has been shown to be chemotactic for lymphocytes4. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells5,6., SDF-1 binding to CXCR4 inhibits HIV-1 entry5,6.
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UniProt
- P48061
抗原
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