beta Amyloid 抗体 (N-Term)
Quick Overview for beta Amyloid 抗体 (N-Term) (ABIN1105355)
抗原
See all beta Amyloid (Abeta) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
特异性
- This antibody recognizes the N-terminal sequence (DAEFRHDS) of beta amyloid peptides, and full length beta amyloid peptide 40, 42 and 43.
-
交叉反应 （详细）
- Species reactivity (tested):Human
-
纯化方法
- Protein G affinity purified
-
免疫原
- Full length human beta amyloid peptide 42
-
亚型
- IgG2b
-
-
anti-Amyloid beta (Abeta) (C-Term) antibody
Abeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 9E8-1A3 unconjugated
anti-Amyloid beta (Abeta) (AA 711-760) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) (Ser15) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人 WB, ELISA, IHC, IP, IEM 宿主: 兔 Chimeric 6E10 unconjugated Recombinant Antibody
anti-Amyloid beta (Abeta) (pThr743) antibodyAbeta 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (Abeta) antibodyAbeta 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal AB9 unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
溶解方式
- Use double distillated water to reconstitute the antibody.
-
缓冲液
- 0.01 M PBS pH 7.2
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C.
-
-
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
-
别名
- Amyloid beta
-
背景
- Beta amyloid, often abbreviated as A-beta, is a protein that builds up in the brains of persons with Alzheimer's disease, collecting in clumps called plaques or senile plaques. While some researchers question whether beta amyloid is the cause of the dementia, most agree that it is involved in the disruption of thinking that is a hallmark of the disease. In some cases of familial Alzheimer's disease, mutations in genes for the proteins called the presenilins lead to increased production of amyloid. Researchers have been looking at how presenilin-1 in particular contributes to the excess buildup of beta amyloid. Presenilin-1 apparently acts to increase the activity of gamma-secretase, an enzyme that changes a normal protein (amyloid precursor protein or APP) into beta amyloid itself. Furthermore, presenilin-1 might be gamma-secretase.
-
基因ID
- 351
-
途径
- Inflammasome
抗原
-
