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AMD1 抗体 (C-Term)

This 兔 多克隆 anti-AMD1 antibody specifically detects AMD1 in WB, IF, IHC (p) 和 IHC (fro). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1105345
发货至: 中国
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Quick Overview for AMD1 抗体 (C-Term) (ABIN1105345)

抗原

See all AMD1 抗体
AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 31
多克隆

标记

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This AMD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects AMD1 (C-term). No cross reactivity with other proteins.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Immunogen affinity purified

    免疫原

    Synthetic peptide corresponding to a sequence at the C-terminal of human SAMDC .Remarks: Sequence is identical to the related mouse and rat sequence.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

    别名

    AMD1

    背景

    S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC), is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.Synonyms: AdoMetDC, S-adenosylmethionine decarboxylase proenzyme, SAMDC

    基因ID

    262

    NCBI登录号

    NP_001625

    UniProt

    P17707

    途径

    Ribonucleoside Biosynthetic Process
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