AGGF1 抗体
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Quick Overview for AGGF1 抗体 (ABIN1105264)
抗原
See all AGGF1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody reacts with human VG5Q, a 84 kDa protein.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Protein A
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免疫原
- VG5Q functions as an angiogenic factor in promoting angiogenesis and suppression of VG5Q expression inhibits vessel formation. Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. Angiogenesis has an essential role in pathological conditions such as cancer and various ischaemic and inflammatory diseases. VG5Q can bind to endothelial cells and promote cell proliferation, suggesting that the protein may act in an autocrine fashion. VG5Q interacts with TWEAK (also known as TNFSF12), another secreted angiogenic factor. VG5Q shows strong expression in blood vessels and is secreted when vessel formation is initiated. VG5Q protein was detected mostly in the cytoplasm and around the nuclei of human microvascular endothelial cells (HMVECs). Furthermore VG5Q is detected in human umbilical vein endothelial cells (HUVECs), human heart fibroblast (HHF) and ovarian cancer cells (OV-3), but low expression was detected in kidney cancer cells (RP-45), HeLa Cells and bladder cancer cells.
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亚型
- IgG
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anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 1-714) antibody
AGGF1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 461-560) antibodyAGGF1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 1-714) antibodyAGGF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 1-70) antibodyAGGF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 263-507) antibodyAGGF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 575-624) antibodyAGGF1 适用: 人, 小鼠, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 406-501) antibodyAGGF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 21-123) antibodyAGGF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1) (AA 470-704) antibodyAGGF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2 - 8 °C.
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- AGGF1 (Angiogenic Factor with G Patch and FHA Domains 1 (AGGF1))
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别名
- AGGF1 / VG5Q
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背景
- Synonyms: Angiogenic factor VG5Q, Angiogenic factor with G patch and FHA domains 1, G patch domain-containing protein 7, GPATC7, GPATCH7, Vasculogenesis gene on 5q protein
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基因ID
- 55109
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NCBI登录号
- NP_060516
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UniProt
- Q8N302
抗原
-
