ACIN1 抗体 (N-Term)
Quick Overview for ACIN1 抗体 (N-Term) (ABIN1105223)
抗原
See all ACIN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-523, N-Term
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特异性
- This antibody reacts withAcinusL.
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交叉反应 （详细）
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Species reactivity (tested):Human.
Does not react with mouse (WR19L, NIH3T3) or hamster (CHO). -
纯化方法
- Protein A agarose beads
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免疫原
- GST-human AcinusL fusion protein corresponding to N-terminal amino acids (1~523 a.a.)
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亚型
- IgG1
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anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) antibody
ACIN1 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2005C3a unconjugated
anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (C-Term) antibodyACIN1 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) antibodyACIN1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (AA 994-1009) antibodyACIN1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (Cytoplasmic Domain) antibodyACIN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (Intermediate Domain) antibodyACIN1 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
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别名
- Acinus / ACIN1
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背景
- Chromatin condensation and nuclear fragmentation (CCNF) are hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase-activated DNase (CAD/DFF40) and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (Apoptotic Chromatin Condensation Inducer in the Nucleus). The 220 kDa Acinus protein is cleaved by caspase-3 and an additional unknown protease to generate a 17 kDa peptide that which causes chromatin condensation in vitro when added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS, and AcinusS'. Acinus is ubiquitously expressed.Synonyms: Apoptotic chromatin condensation inducer in the nucleus, KIAA0670
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分子量
- 220 kDa
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基因ID
- 22985
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NCBI登录号
- NP_001158286
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UniProt
- Q9UKV3
抗原
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