14-3-3 Pan 抗体
This anti- antibody is a 小鼠 单克隆 antibody detecting in WB. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for 14-3-3 Pan 抗体 (ABIN1105134)
抗原
14-3-3 Pan
适用
人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Western Blotting (WB)
克隆位点
3C8
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Protein A agarose
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免疫原
- Recombinant human 14-3-3beta
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亚型
- IgG2b
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anti-14-3-3 Pan (AA 174-245) antibody
适用: 人, 小鼠, 大鼠, Saccharomyces cerevisiae WB, IF (p), IHC (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2, containing no preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- 14-3-3 Pan
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别名
- 14-3-3 Protein Pan
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背景
- 14-3-3 was first described as an abundant acidic protein in brain composing 1 % of the total soluble protein. The 14-3-3 family of proteins are expressed in all eukaryotic cells. There are at least seven highly conserved isoforms encoded by different gene products. These proteins have molecular weights of 29,000-32,000 and bind numerous cytoplasmic and nuclear signaling molecules including signaling molecules such as Raf, protein kinase C, p130Cas, BAD, and phosphatidylinositol 3-kinase. Interaction of 14-3-3 proteins with signaling molecules can localize, activate, inhibit, or stabilize the target molecules. Because 14-3-3 proteins are homo- and heterodimers, they have been considered as adaptor proteins that recruit and regulate the function of signaling molecules. They have been implicated in regulation of cell proliferation, cell cycle progression, apoptosis, and differentiation.
抗原
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