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Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) 抗体

This 小鼠 单克隆 antibody specifically detects Cav3.1 Ca2+ Channel in IHC, WB 和 IF/ICC. It exhibits reactivity toward 小鼠.
产品编号 ABIN1098196
发货至: 中国
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Quick Overview for Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) 抗体 (ABIN1098196)

抗原

Cav3.1 Ca2+ Channel

适用

  • 6
  • 1
  • 1
小鼠

宿主

  • 7
小鼠

克隆类型

  • 7
单克隆

标记

  • 3
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 7
  • 5
  • 3
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

克隆位点

S178A-9
  • 抗原表位

    • 6
    • 6
    • 5
    AA 2052-2172, C-Term

    原理

    Anti-Cav3.1 Ca+2 Channel Mouse Monoclonal Antibody

    特异性

    This antibody recognizes human, mouse, and rat Cav3.1. It does not cross-react with Cav3.2.

    交叉反应

    人, 小鼠, 大鼠

    交叉反应 (详细)

    No cross Reactivity with Cav3.2

    纯化方法

    Purified by Protein G affinity chromatography.

    免疫原

    Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).

    亚型

    IgG1
  • 应用备注

    Immunoblotting: use at 1-2 μg/mL. A band of >200 kDa is detected.
    Immunohistochemistry: use at 1-10 μg/mL.
    These are recommended concentrations. User should determine optimal concentrations for their application.
    Positive control: Rat brain membranes.

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Dilute in PBS or medium which is identical to that used in the assay system.

    浓度

    Lot specific

    缓冲液

    PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    This antibody is stable for at least one (1) year at -20°C.
  • 抗原

    Cav3.1 Ca2+ Channel

    别名

    Cav3.1 Ca+2 Channel

    背景

    Voltage-dependent T-type calcium channel subunit α,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage- activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and antiepileptics and possibly in some anesthetics and antipsychotics.

    NCBI登录号

    NP_001106284

    UniProt

    Q9WUT2
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