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Prosaposin 抗体 (AA 325-524)

Name: Prosaposin 抗体 (AA 325-524)
Brand: antibodies-online
SKU: ABIN1098150
Availability: OutOfStock

This anti-Prosaposin antibody is a 小鼠单克隆 antibody detecting Prosaposin in IHC, ELISA, ICC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

mmunohistochemical analysis of paraffin-embedded pancreas tissues using PSAP mouse mAb with DAB staining. (Prosaposin 抗体 (AA 325-524))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Prosaposin 抗体 (AA 325-524))

ELISA

Flow cytometric analysis of HeLa cells using PSAP mouse mAb (green) and negative control (purple). (Prosaposin 抗体 (AA 325-524))

FACS

Western blot analysis using PSAP mAb against human PSAP recombinant protein. (Prosaposin 抗体 (AA 325-524))

Immunofluorescence analysis of HepG2 cells using PSAP mouse mAb (green). (Prosaposin 抗体 (AA 325-524))

Western blot analysis using PSAP mAb against HEK293 (1) and PSAP (AA: 325-524)-hIgGFc transfected HEK293 (2) cell lysate. (Prosaposin 抗体 (AA 325-524))

6 images

(2 references)

产品编号 ABIN1098150

发货至: 中国

Quick Overview for Prosaposin 抗体 (AA 325-524) (ABIN1098150)

抗原

See all Prosaposin (PSAP) 抗体

Prosaposin (PSAP)

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This Prosaposin antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

4D5F4

抗原表位
15

7

6

4

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 325-524

原理

PSAP Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. Coli.

亚型

IgG1
anti-Prosaposin (PSAP) (AA 17-524) antibody
PSAP 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Prosaposin (PSAP) (AA 60-310) antibody
PSAP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Prosaposin (PSAP) (AA 17-216) antibody
PSAP 适用: 人, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3B4A8 unconjugated

anti-Prosaposin (PSAP) (AA 18-524) antibody
PSAP 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D1-C12 unconjugated

anti-Prosaposin (PSAP) (AA 325-524) antibody
PSAP 适用: 人 WB, IHC, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-Prosaposin (PSAP) (AA 311-391) antibody
PSAP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Prosaposin (PSAP) (AA 1-524) antibody
PSAP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F6 unconjugated

anti-Prosaposin (PSAP) (Internal Region) antibody
PSAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Prosaposin (PSAP) antibody
PSAP 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-452M unconjugated Recombinant Antibody

anti-Prosaposin (PSAP) (AA 18-525) antibody
PSAP 适用: 人 WB, IHC, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D1-C12 unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/500

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Xu, Deng, Mao, Zhang, Wang, Wang, Mu, Deng, Ma: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).

Hu, Delorme, Liu, Liu, Velasco-Gonzalez, Garai, Pullikuth, Koochekpour: "Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion." in: Molecular cancer, Vol. 9, pp. 30, (2010) (PubMed).
抗原

Prosaposin (PSAP)

别名

PSAP

背景

This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

分子量

58.1 kDa

UniProt

P07602

途径

Positive Regulation of Endopeptidase Activity