Prosaposin 抗体 (AA 325-524)
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北京 101111
Quick Overview for Prosaposin 抗体 (AA 325-524) (ABIN1098150)
抗原
See all Prosaposin (PSAP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 325-524
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原理
- PSAP Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. Coli.
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亚型
- IgG1
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anti-Prosaposin (PSAP) (AA 17-524) antibody
PSAP 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 60-310) antibodyPSAP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 17-216) antibodyPSAP 适用: 人, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3B4A8 unconjugated
anti-Prosaposin (PSAP) (AA 18-524) antibodyPSAP 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D1-C12 unconjugated
anti-Prosaposin (PSAP) (AA 325-524) antibodyPSAP 适用: 人 WB, IHC, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Prosaposin (PSAP) (AA 311-391) antibodyPSAP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (full length) antibodyPSAP 适用: 人 IHC 宿主: 小鼠 Monoclonal 452M unconjugated Recombinant Antibody
anti-Prosaposin (PSAP) (Internal Region) antibodyPSAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 1-524) antibodyPSAP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Prosaposin (PSAP) (AA 18-525) antibodyPSAP 适用: 人 WB, IHC, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D1-C12 unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).
: "Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion." in: Molecular cancer, Vol. 9, pp. 30, (2010) (PubMed).
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: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).
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- Prosaposin (PSAP)
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别名
- PSAP
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背景
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This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 58.1 kDa
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UniProt
- P07602
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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