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Surfactant Protein C 抗体 (AA 60-180)

This anti-Surfactant Protein C antibody is a 小鼠 单克隆 antibody detecting Surfactant Protein C in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1098147
发货至: 中国

Quick Overview for Surfactant Protein C 抗体 (AA 60-180) (ABIN1098147)

抗原

See all Surfactant Protein C (SFTPC) 抗体
Surfactant Protein C (SFTPC)

适用

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  • 34
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宿主

  • 70
  • 11
小鼠

克隆类型

  • 72
  • 9
单克隆

标记

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  • 4
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Surfactant Protein C antibody is un-conjugated

应用范围

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  • 34
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  • 21
  • 15
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  • 3
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  • 1
ELISA

克隆位点

5E6A9
  • 抗原表位

    • 18
    • 11
    • 8
    • 6
    • 5
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
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    • 1
    AA 60-180

    原理

    SFTPC Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human SFTPC (AA: 60-180 ) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zhong, Zhou, Ann, Minoo, Liu, Banfalvi, Krishnaveni, Dubourd, Demaio, Willis, Kim, duBois, Crandall, Beers, Borok: "Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein." in: American journal of respiratory cell and molecular biology, Vol. 45, Issue 3, pp. 498-509, (2011) (PubMed).

    Wang, Bridges, Na, Xu, Weaver: "Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33377-83, (2009) (PubMed).

  • 抗原

    Surfactant Protein C (SFTPC)

    别名

    SFTPC

    背景

    This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

    分子量

    21 kDa

    UniProt

    P11686
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