ACLY 抗体 (AA 306-502)
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北京 101111
Quick Overview for ACLY 抗体 (AA 306-502) (ABIN1098143)
抗原
See all ACLY 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 306-502
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原理
- ACLY Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human ACLY (AA: 306-502 ) expressed in E. Coli.
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亚型
- IgG1
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anti-ATP Citrate Lyase (ACLY) (AA 752-1101) antibody
ACLY 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (pSer455) antibodyACLY 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 306-502) antibodyACLY 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) (AA 4-265) antibodyACLY 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyACLY 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyACLY 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Monoclonal 3A5 unconjugated Recombinant Antibody
anti-ATP Citrate Lyase (ACLY) (C-Term) antibodyACLY 适用: 人, 小鼠 WB, FACS, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyKD Validated ACLY 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1620 unconjugated Recombinant Antibody
anti-ATP Citrate Lyase (ACLY) (Middle Region) antibodyACLY 适用: 人, 小鼠, 大鼠, Pig, Cow, 兔, 斑马鱼, 绵羊, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATP Citrate Lyase (ACLY) antibodyACLY 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells." in: The Journal of biological chemistry, Vol. 285, Issue 42, pp. 32606-15, (2010) (PubMed).
: "Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 10, pp. 2282-95, (2010) (PubMed).
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: "ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells." in: The Journal of biological chemistry, Vol. 285, Issue 42, pp. 32606-15, (2010) (PubMed).
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- ACLY (ATP Citrate Lyase (ACLY))
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别名
- ACLY
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背景
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ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
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分子量
- 125 kDa
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基因ID
- 47
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UniProt
- P53396
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途径
- Warburg Effect
抗原
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