LMO2 抗体 (AA 1-158)
Quick Overview for LMO2 抗体 (AA 1-158) (ABIN1098128)
抗原
See all LMO2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-158
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原理
- LMO2 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).
: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).
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: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).
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- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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别名
- LMO2
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背景
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LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 18.4 kDa
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UniProt
- P25791
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途径
- Chromatin Binding
抗原
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