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LMO2 抗体 (AA 1-158)

Cited in 2+ publications. This anti-LMO2 antibody is a 小鼠 单克隆 antibody detecting LMO2 in FACS 和 ELISA. Suitable for 人.
产品编号 ABIN1098128
发货至: 中国
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中国
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Room 801-803
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Quick Overview for LMO2 抗体 (AA 1-158) (ABIN1098128)

抗原

See all LMO2 抗体
LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

适用

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  • 3
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宿主

  • 56
  • 29
  • 2
  • 2
小鼠

克隆类型

  • 55
  • 34
单克隆

标记

  • 47
  • 6
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  • 3
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This LMO2 antibody is un-conjugated

应用范围

  • 60
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  • 34
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  • 11
  • 2
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Flow Cytometry (FACS), ELISA

克隆位点

4D8
  • 抗原表位

    • 34
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    • 2
    • 2
    • 1
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    • 1
    AA 1-158

    原理

    LMO2 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Cubedo, Maurin, Jiang, Lossos, Wright: "PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL." in: The FEBS journal, Vol. 278, Issue 17, pp. 3065-75, (2011) (PubMed).

    Baecklund, Backlin, Mansouri, Klareskog, Askling, Iliadou, Enblad, Lossos, Natkunam, Rosenquist: "LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma." in: Leukemia & lymphoma, Vol. 52, Issue 6, pp. 1146-9, (2011) (PubMed).

  • 抗原

    LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

    别名

    LMO2

    背景

    LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    18.4 kDa

    UniProt

    P25791

    途径

    Chromatin Binding
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