ILK 抗体 (AA 97-244)
Quick Overview for ILK 抗体 (AA 97-244) (ABIN1098122)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 97-244
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原理
 - ILK Antibody
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纯化方法
 - Ascitic fluid
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免疫原
 - Purified recombinant fragment of human ILK (AA: 97-244) expressed in E. Coli.
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亚型
 - IgG1
 
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - Ascitic fluid containing 0.03 % sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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                                            : "Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells."    in: Surgery, Vol. 150, Issue 2, pp. 162-8, (2011)         (PubMed).        
: "The importance of integrin-linked kinase in the regulation of bladder cancer invasion." in: International journal of cancer. Journal international du cancer, Vol. 130, Issue 3, pp. 521-31, (2011) (PubMed).
 
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                                            : "Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells."    in: Surgery, Vol. 150, Issue 2, pp. 162-8, (2011)         (PubMed).        
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- ILK (Integrin-Linked Kinase (ILK))
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别名
 - ILK
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背景
 - Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
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分子量
 - 51.4 kDa
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基因ID
 - 3611
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UniProt
 - Q13418
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途径
 - Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
 
抗原
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