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CSNK2A2 抗体 (AA 194-350)

This anti-CSNK2A2 antibody (ABIN1098114) is a Mouse Monoclonal antibody detecting CSNK2A2 in WB, ELISA, FACS. Suitable for Human, Mouse.
产品编号 ABIN1098114
发货至: 中国

Quick Overview for CSNK2A2 抗体 (AA 194-350) (ABIN1098114)

抗原

See all CSNK2A2 抗体
CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

适用

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人, 小鼠

宿主

  • 38
  • 2
小鼠

克隆类型

  • 38
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单克隆

标记

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This CSNK2A2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

1E1
  • 抗原表位

    • 8
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    AA 194-350

    原理

    CSNK2A2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Chemnitz, Pieper, Grüttner, Hauber: "Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression." in: European journal of immunology, Vol. 39, Issue 1, pp. 267-79, (2009) (PubMed).

    Schäfer, Götz, Dudek, Hessenauer, Matti, Montenarh: "KIF5C: a new binding partner for protein kinase CK2 with a preference for the CK2alpha' subunit." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 2, pp. 339-49, (2009) (PubMed).

  • 抗原

    CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

    别名

    CSNK2A2

    背景

    Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt.

    分子量

    41.2 kDa

    基因ID

    1459

    UniProt

    P19784

    途径

    SARS-CoV-2 Protein Interactome
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