PIK3R1 抗体 (AA 159-388)
Quick Overview for PIK3R1 抗体 (AA 159-388) (ABIN1098111)
抗原
See all PIK3R1 (PI3K p85a) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 159-388
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原理
- PIK3R1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human PIK3R1 (AA: 159-388) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques. ..." in: Molecular neurodegeneration, Vol. 15, Issue 1, pp. 66, (2020) (PubMed).
: "Genetic polymorphisms in inflammation pathway genes and prostate cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 20, Issue 5, pp. 923-33, (2011) (PubMed).
: "The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling." in: Cancer research, Vol. 70, Issue 13, pp. 5305-15, (2010) (PubMed).
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Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques. ..." in: Molecular neurodegeneration, Vol. 15, Issue 1, pp. 66, (2020) (PubMed).
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- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
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别名
- PIK3R1
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背景
- Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.
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分子量
- 83.6 kDa
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基因ID
- 5295
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UniProt
- P27986
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途径
- TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect
抗原
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