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PIK3R1 抗体 (AA 159-388)

This anti-PIK3R1 antibody is a 小鼠 单克隆 antibody detecting PIK3R1 in ELISA, IHC, FACS 和 ICC. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1098111
发货至: 中国

Quick Overview for PIK3R1 抗体 (AA 159-388) (ABIN1098111)

抗原

See all PIK3R1 (PI3K p85a) 抗体
PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

适用

  • 133
  • 93
  • 70
  • 17
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  • 2
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  • 2
  • 2
  • 1
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人, 小鼠

宿主

  • 117
  • 29
小鼠

克隆类型

  • 100
  • 46
单克隆

标记

  • 81
  • 10
  • 8
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  • 3
  • 3
  • 2
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  • 2
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  • 2
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  • 2
This PIK3R1 antibody is un-conjugated

应用范围

  • 117
  • 59
  • 44
  • 28
  • 21
  • 19
  • 17
  • 16
  • 12
  • 7
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

6G10
  • 抗原表位

    • 19
    • 15
    • 15
    • 10
    • 9
    • 9
    • 8
    • 5
    • 5
    • 4
    • 4
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 159-388

    原理

    PIK3R1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human PIK3R1 (AA: 159-388) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Natunen, Martiskainen, Marttinen, Gabbouj, Koivisto, Kemppainen, Kaipainen, Takalo, Svobodová, Leppänen, Kemiläinen, Ryhänen, Kuulasmaa, Rahunen, Juutinen, Mäkinen, Miettinen, Rauramaa, Pihlajamäki et al.: "Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques. ..." in: Molecular neurodegeneration, Vol. 15, Issue 1, pp. 66, (2020) (PubMed).

    Kwon, Salinas, Kolb, Fu, Feng, Stanford, Ostrander: "Genetic polymorphisms in inflammation pathway genes and prostate cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 20, Issue 5, pp. 923-33, (2011) (PubMed).

    Taniguchi, Winnay, Kondo, Bronson, Guimaraes, Alemán, Luo, Stephanopoulos, Weissleder, Cantley, Kahn: "The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling." in: Cancer research, Vol. 70, Issue 13, pp. 5305-15, (2010) (PubMed).

  • 抗原

    PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

    别名

    PIK3R1

    背景

    Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

    分子量

    83.6 kDa

    基因ID

    5295

    UniProt

    P27986

    途径

    TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect
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